The Register's Annual Great Bicycle Ride Across Iowa begins July 22nd in Sioux Center, with the first overnight stop in Cherokee.

The RAGBRAI route was announced over the weekend.

From there the bikers proceed through Lake View, Webster City, Marshalltown, Cedar Rapids, Anamosa and finally Clinton on July 28th.

Host cities will start working with ride officials right away to determine the best ways to handle over 20-thousand bicyclists, support crews and spectators.

Kent Harfst is the parks and recreation director in Webster City, one of the midweek host cities.

This will be the 40th year for the statewide ride which brings pedalers from around the world for the weeklong trek across Iowa. This year's event will run 471 miles from Sioux County near the Missouri River to the Mississippi River.

Radio Iowa contributed to this story

Two Sioux City residents died and another was injured during a crash on Interstate 80 Sunday morning about a mile east of Casey in Adair County.

The Iowa State Patrol says 58-year-old Cynthia Piester, and her daughter, 38-year-old Jennifer Piester, died in the crash.

Cynthia's husband, 60-year-old Johnny Piester, who was driving the SUV, was injured, and transported by Stuart Rescue to Mercy Hospital in Des Moines, where he was listed in fair condition Sunday night.

Officials say Piester's 2000 Chevy Trail Blazer was traveling east on I-80 at around 10:50-a.m., when, for reasons unknown, the SUV entered the median, went between the bridges of the Middle River, and came into contact with the rock embankment.

The vehicle rolled onto its roof, made contact with the west bank of the river, and slid across the river ice before coming to rest partially submerged on the east bank of the river.

All three of the accident victims were wearing their seatbelts. The accident remains under investigation.

A LANE CLOSURE ON PIERCE STREET WILL BEGIN NEXT WEEK IN SIOUX CITY.

THE EAST, OR OUTSIDE, LAND OF PIERCE STREET BETWEEN 13TH AND 14TH WILL BE CLOSED MONDAY AND TUESDAY TO ALLOW WATER LINE WORK.

YOU ARE ADVISED TO USE CAUTION AROUND THIS AREA AND OBEY ALL SIGNS AND BARRICADES WITH REGARD TO THIS WORK.

 SAC COUNTY AUTHORITIES SAY NO CHARGES HAVE BEEN FILED YET IN AN ALLEGED ANIMAL ABUSE CASE NEAR KIRON, IOWA.

88 DOGS AND ONE CAT WERE RESCUED BY AUTHORITIES FROM A DOG BREEDER'S PROPERTY THERE THURSDAY MORNING. FIVE DOGS WERE FOUND DEAD AT THE RURAL PROPERTY OWNED BY MARY BRODERSON.

CHIEF DEPUTY SCOTT BROUWER SAYS AUTHORITES MADE THREE VISITS IN TEN DAYS TO THE PROPERTY, BUT WERE UNABLE TO LOCATE BRODERSON, OR ANY OTHER PERSON ON THE PROPERTY.

BRODERSON IS NOT LICENSED BY THE USDA TO SELL ANY OF THE DOGS. THE DOGS WERE MAINLY COCKER SPANIELS AND 14 ARE BEING CARED FOR IN SIOUX CITY.

THE INVESTIGATION OF THE CASE IS CONTINUING.