American Red Cross units from Sioux City, Des Moines and three other Iowa locations are on their way to Colorado to assist with flood relief.
Colorado has asked for all five regional emergency response vehicles from Iowa to respond as soon as possible.
A two person crew from Sioux City left Monday morning.
Red Cross volunteers are staffing shelters or evacuation centers throughout Colorado.
The Red Cross says about 1,250 people stayed in 26 shelters Saturday night.
The organization also is helping other organizations plan for recovery which includes assessing damage and providing cleanup supplies.